Francis J. Hart
390 Ryan Road
Pea Ridge, AR 72751
479 451-8517
October 3, 2003
Senator Blanche Lambert Lincoln
Senator Mark Pryor
Representative John Boozman
This method of contacting you was selected due to the explosive potential of this matter and lack of a direct email address.
After extensive research and testing my findings on individuals knowledgeable and experienced in the appropriate field, I can tell say there is a flaw in the FDA test management program relative to environmental stress on human performance.
The critical item involved in this finding is oxalic acid, a blood borne chemical in the blood of all mammals including humans. A estimated mean value of 288mcg of anhydrous oxalic acid/100ml has been reported for normal human blood.
The decomposition of solutions of oxalic acid has been made a basis of a method for measuring radiation dosage, in the sterilization of food and medical products. The absorbed dose is determined from the decrease in oxalic acid concentration which occurs during irradiation.
If the FDA authorizes a new drug for use on humans or other mammals, where the approved test procedure was directed toward identification of potential failure of the drug and irradiation was used partially or continuously on a mammalian test specimen, the test is flawed. It is possible very serious consequences could develop if a human with a normal or elevated oxalic acid blood level was provided the drug. If oxalic acid and the new drug created a toxic chemical it would not be known. The results could have lethal consequences.
Immediate action should be taken to confirm or deny my findings. Approval of any product where radiation was used during testing should be immediately suspended until the action is completed.
Respectfully
signed
Francis J. Hart
Lt Col USAF ret.